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Study identifier: NCT06380192 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Developmental and Epileptic Encephalopathy of Genetic Etiology: Natural History Through Reuse of Clinical Data

Condition: Developmental and Epileptic Encephalopathy  ·  Sponsor: Imagine Institute

PhaseN/A
Planned participants400
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

Developmental and Epileptic Encephalopathy (DEE) are a heterogeneous group of neurodevelopmental disorders linked to both epilepsy and its underlying etiology, independently of epileptiform activity. The creation of a database with retrospective follow-up of a large number of patients on a national scale will enable better knowledge of specific biomarkers, and thus a better classification and understanding of the natural evolution of DEE according to their etiology. This will enable better, more personalized therapeutic management of patients, depending on etiology and the presence or absence of these biomarkers. The investigators will also be able to draw up management recommendations, which are currently non-existent.

This description comes directly from the study's public registry record.

Talk to the study team

Rima Nabbout, Pr  ·  +33144381536  ·  rima.nabbout@aphp.fr

Always discuss trial participation with your own doctor first.

Locations (23)

CHU AmiensAmiens, FranceNot Yet Recruiting
CH AngersAngers, FranceNot Yet Recruiting
Chu BesanconBesançon, FranceNot Yet Recruiting
CHU BordeauxBordeaux, FranceNot Yet Recruiting
CHRU BrestBrest, FranceNot Yet Recruiting
CHU Clermont-FerrandClermont-Ferrand, FranceNot Yet Recruiting
CHU GrenobleGrenoble, FranceNot Yet Recruiting
CHU LilleLille, FranceNot Yet Recruiting
CHU LimogesLimoges, FranceNot Yet Recruiting
CHU Lyon HCLLyon, FranceNot Yet Recruiting
Assistance Publique Hopitaux de MarseilleMarseille, FranceNot Yet Recruiting
CHU de NancyNancy, FranceNot Yet Recruiting

+ 11 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06380192