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Study identifier: NCT06380114 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Stand Up 2 HPV: Standing Orders to Improve HPV Vaccination

Condition: Hpv  ·  Sponsor: University of Rochester

PhaseNA
Planned participants16000
Who can joinAll sexes, 9 Years to 17 Years
Healthy volunteersYes

About this study

Each year in the U.S., ≥20,000 women and 14,000 men are affected by HPV-related cancers, including cervical and oropharyngeal cancer. However, in 2020, only 59% of U.S. adolescents aged 13-17 were up-to-date for HPV vaccination, and rates for 11-12 year olds, the primary target age group for HPV vaccination (when the immune reaction is better and before exposure to HPV infection), are even lower. Standing orders (written protocols that authorize designated members of the healthcare team to vaccinate without first obtaining a patient-specific physician order) have been shown to work in inpatient settings and for adults, but have not been evaluated for HPV vaccine, which some parents consider controversial. Also, the ways in which organizational readiness for change (resources, motivation, staff attributes, leadership support and culture) moderate the effect of standing orders has not been studied. A physician's recommendation is correlated with HPV vaccine acceptance, and the investigators have developed a successful online, interactive, communication education program that will be adapted to train nurses and staff in addition to physicians. The investigators propose testing standing orders for HPV vaccine in an Accountable Care Organization (ACO) in Western New York, and assessing which provider and practice factors moderate the effect of standing orders. Advantages of this setting include a diverse group of rural, urban and suburban practices, and the ACO provides data infra…

This description comes directly from the study's public registry record.

Talk to the study team

Robin Bender  ·  (585) 274-1499  ·  robin_bender@urmc.rochester.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Rochester Medical Center (URMC)Rochester, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06380114