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Study identifier: NCT06376214 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Daratumumab for Patients With Light Chain Amyloidosis

Condition: Light Chain (AL) Amyloidosis  ·  Sponsor: Nanjing University School of Medicine

PhaseNA
Planned participants100
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This is a prospective, single-center study exploratory clinical trial, aim to exploring the efficacy and safety of daratumumab in patients with AL amyloidosis, patients were divided into three groups: one group received long-term treatment with daratumumab based regimen, and the other group received autologous stem cell transplantation after two standard treatment courses with daratumumab based regimen, and the third group consists of newly diagnosed stage IIIb AL amyloidosis patients who plan to receive DPD treatment. The purpose of this study is to observe the efficacy and safety of Daratumumab, in the treatment of newly diagnosed systemic AL amyloidosis.

This description comes directly from the study's public registry record.

Talk to the study team

Xianghua Huang, MD  ·  02580862351  ·  hxhszb@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

National Clinical Research Center for Kidney Diseases, Jinling HospitalNanjing, Jiangsu, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06376214