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Study identifier: NCT06373679 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Switch or Quit R01

Condition: Cigarette Smoking · Smoking Behaviors  ·  Sponsor: Medical University of South Carolina

PhaseNA
Planned participants225
Who can joinAll sexes, 21 Years to no upper limit
Healthy volunteersYes

About this study

This study evaluates whether non-cigarette tobacco products (e-cigarettes) can help smokers quit smoking as compared to traditional quit methods (nicotine replacement therapy or varenicline/Chantix). Participants in this study will be randomly assigned to one of two groups, then will have a choice between the offered products of that group. Participants in the e-cigarette group will have a choice of e-cigarette brand and flavor. Participants in the medication group will have choice between nicotine replacement therapy (patches and lozenges) or varenicline, also known as Chantix. Participation will last 6 months and will include weekly phone calls for the initial 7-weeks plus a 11-week phone call and a 6-month follow-up visit. Participants will also complete electronic daily diaries during the first 7-weeks.

This description comes directly from the study's public registry record.

Talk to the study team

Tracy Smith, PhD  ·  (843)-792-5164  ·  smithtra@musc.edu

Hana Thamer  ·  (843)-876-2430  ·  thamer@musc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Medical Univeristy of South CarolinaCharleston, South Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06373679