Condition: E-cigarette Use · Cigarette Smoking · Harm Reduction · Sponsor: Abramson Cancer Center at Penn Medicine
This between-subjects study aims to evaluate whether e-cigarettes (ECIGS) versus oral nicotine pouches (ONPS) more readily substitute for combustible cigarettes among 200 cigarette smokers. After measuring baseline cigarette smoking rate, participants will be randomized to ECIGS or ONPS and be instructed to switch (versus smoking cigarettes) over a 6-week period. Relative reductions in biomarkers of exposure will be measured. ECIG- and ONP-associated subjective reward and the reinforcing value of ECIGS and ONPS relative to combustible cigarettes will be assessed as mechanisms.
This description comes directly from the study's public registry record.
Janet Audrain-McGovern, Ph.D. · 215-746-7145 · audrain@pennmedicine.upenn.edu
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| University of Pennsylvania | Philadelphia, Pennsylvania, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06372899