Condition: Myasthenia Gravis · Sponsor: Ting Chang, MD
This study is a single-center, open-label, single-arm, dose-exploration study to evaluate the safety and preliminary effectiveness of CD19-BCMA CAR-T in the treatment of refractory, generalized myasthenia gravis. The study is a dose escalation trial in adult, refractory, systemic MG patients. The Keyboard method will be used to perform dose escalation to explore the maximum tolerated dose (MTD). A total of 12 MG patients who meet the inclusion criteria are expected to be recruited.
This description comes directly from the study's public registry record.
Zhe Ruan · 8618682932643 · ruanzhe573291596@126.com
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| Tangdu Hospital, The Fourth Military Medical University | Xi'an, Shaanxi, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06371040