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Study identifier: NCT06370923 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Harnessing Male Peer Networks to Enhance Engagement With HIV Prevention

Condition: HIV Infections  ·  Sponsor: University of Stellenbosch

PhaseNA
Planned participants3591
Who can joinMale, 18 Years to no upper limit
Healthy volunteersYes

About this study

Novel strategies are needed to engage men in Sub Saharan Africa (SSA) with HIV testing, treatment and prevention services to drive the epidemic towards elimination. Suboptimal engagement with HIV prevention by men increases their risk of HIV acquisition, and is an important driver of new HIV infections in women. HIV self-testing (HIVST) addresses several key facility-based access barriers and HIVST distribution through leveraging male peer networks for HIV prevention is feasible, acceptable and effective in SSA. The objective of this project is to use an implementation science approach to establish the impact of HIVST distribution through male social networks, with phone-based support and improved risk perception, on PrEP (Pre-Exposure Prophylaxis) uptake among men in Eastern Zimbabwe. The project will leverage infrastructure and data associated with 20-year programme of HIV surveillance and behavioural research in a well-characterized population cohort hosted by the Manicaland Centre for Public Health Research, Zimbabwe. The study will utilise a cluster randomised design of 44 clusters (22 Intervention:22 control) comprising on average 81 men in each cluster (total N = 3591) followed for 6 months (giving \>80% power to detect a difference in PrEP initiation among men of 2% versus 8.5%). In intervention clusters the investigators will identify initial distributors who will receive an HIVST kit for personal use and HIVST kits to distribute to local peers. These peers can sub…

This description comes directly from the study's public registry record.

Talk to the study team

Constance Nyamukapa, PhD  ·  +263 71 480 4050  ·  nyamukapaconnie@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

BRTI - Manicaland Centre for Public Health ResearchMutare, Manicaland Province, ZimbabweRecruiting

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Source record: clinicaltrials.gov/study/NCT06370923