Condition: Bronchiectasis · Sponsor: Centre Hospitalier Intercommunal Creteil
Chronic airways infection with Pseudomonas aeruginosa (PA) is associated with increased frequency of exacerbations, deterioration in quality of life and increased mortality in adult patients with bronchiectasis. Current guidelines suggest the prescription of an eradication antibiotic treatment for a first episode of PA infection (early PA infection). Several antibiotic regimens may be proposed, ranging from a monotherapy with oral fluoroquinolone (FQ) to an intravenous cotherapy with the addition of inhaled antibiotics that seems to improve the rate of PA eradication. As no study strictly favoured one regimen, current practices are heterogeneous and could certainly benefit from stronger evidence, with both medical and economic impact.
This description comes directly from the study's public registry record.
Camille JUNG, MD · 0157022000 · camille.jung@chicreteil.fr
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| CHU Amiens-Picardie | Amiens, France | Recruiting |
| CHU Haut Leveque, Bordeaux | Bordeaux, France | Recruiting |
| CHRU Brest | Brest, France | Recruiting |
| CH Pontoise | Cergy-Pontoise, France | Recruiting |
| Centre hospitalier intercommunal de Créteil | Créteil, France | Recruiting |
| APHP, Henri Mondor | Créteil, France | Recruiting |
| Hôpital de la Croix Rousse, HCL, Lyon | Lyon, France | Not Yet Recruiting |
| Clinique St Joseph | Marseille, France | Recruiting |
| CHU Nantes | Nantes, France | Recruiting |
| CHU H. Pasteur, Nice | Nice, France | Not Yet Recruiting |
| Hôpital Pitié Salpêtrière | Paris, France | Recruiting |
| APHP, Cochin | Paris, France | Recruiting |
+ 6 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06368804