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Study identifier: NCT06367972 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Randomized Phase II Basket Trial EXTENDing Efficacy of Systemic Therapy With Local Consolidative Therapy for OligoProgressive Metastatic Disease (EXTEND-OP)

Condition: OligoProgressive Metastatic Disease  ·  Sponsor: M.D. Anderson Cancer Center

PhasePhase 2/Phase 3
Planned participants400
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

To find out if local consolidation therapy (such as radiation therapy with or without other local therapies such as surgery, ablation \[the removal or destruction of a body part or tissue or its function\], or embolization \[a procedure that uses particles, such as tiny gelatin sponges or beads, to block a blood vessel\]) to all progressive sites of disease can help to control the disease compared with next-line systemic therapy.

This description comes directly from the study's public registry record.

Talk to the study team

Ethan Ludmir, MD  ·  (832) 729-0998  ·  ebludmir@mdanderson.org

Always discuss trial participation with your own doctor first.

Locations (1)

MD Anderson Cancer CenterHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06367972