Condition: Video-assisted Thoracoscopic Lung Surgery；Anesthesia · Sponsor: Tongji Hospital
Non-tracheal intubated combined anesthesia with preserved spontaneous breathing significantly enhances the quality and speed of recovery post-VATS for patients undergoing lung nodule surgery. The "opioid-sparing strategy," which substitutes ketamine for opioids during surgery, not only provides effective analgesia but also protects perioperative lung function and reasonably prevents the occurrence of opioid-related adverse reactions; it also reduces medical costs and shortens the average hospital stay. However, the degree of benefit to patients lacks high-level clinical evidence. This study aims to comprehensively assess the effect of opioid-free combined anesthesia with preserved spontaneous breathing for VATS lung nodule surgery on postoperative rapid recovery from multiple aspects including postoperative lung function and pulmonary complications, pain, gastrointestinal function, nausea/vomiting, cognitive function, and depression/anxiety, intending to expand the dataset and application prospects in this field, and increase feasibility experience.
This description comes directly from the study's public registry record.
Hui Xu, Professor · (86)-13971001596 · huixu@tjh.tjmu.edu.cn
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| Tongji Hospital | Wuhan, Hubei, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06367218