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Study identifier: NCT06366399 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The Acute T-Rex (Timing of Resistance Exercise) Study

Condition: Diabetes Mellitus, Type 2 · Insulin Resistance · Glucose Intolerance  ·  Sponsor: University of Utah

PhaseNA
Planned participants20
Who can joinAll sexes, 50 Years to 74 Years
Healthy volunteersNo

About this study

The primary aim of this study is to evaluate if a single bout of AM vs PM resistance exercise has different effects on insulin sensitivity and sleep. A randomized cross-over trial be used to compare resistance exercise at two different times of the day. Each condition will take place in a laboratory setting. Each condition will consist of exercise, overnight sleep, and oral glucose tolerance tests the following day. The AM exercise will occur \~1.5 hours after habitual wake, and PM exercise will occur \~11 hours after habitual wake. After a 2-6 week washout, participants will complete the other condition. The hypothesis is that PM exercise will be more beneficial than AM exercise in improving insulin sensitivity. This study could identify if there is a better time of day to perform resistance exercise to decrease risk of developing Type 2 Diabetes Mellitus.

This description comes directly from the study's public registry record.

Talk to the study team

Tanya M Halliday, PhD  ·  801-213-1364  ·  tanya.halliday@utah.edu

Study Email Study Email  ·  8014487897  ·  trexstudy@utah.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Utah HPER E BuildlingSalt Lake City, Utah, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06366399