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Study identifier: NCT06365853 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Ocular Toxicity Evaluation and Mitigation During Treatment With Mirvetuximab Soravtansine in Participants With Recurrent Ovarian Cancer With High Folate Receptor-Alpha Expression

Condition: Recurrent Ovarian Cancer · Folate Receptor-Alpha Positive  ·  Sponsor: AbbVie

PhasePhase 2
Planned participants100
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the incidence rate and severity of prespecified mirvetuximab soravtansine (MIRV)-related ocular treatment-emergent adverse events (TEAEs) and assess prophylaxis strategies in all participants (symptomatic and asymptomatic) undergoing prospective ophthalmic evaluation with recurrent ovarian cancer (participants with either platinum-sensitive ovarian cancer \[PSOC\] or platinum-resistant ovarian cancer \[PROC\]) with high folate receptor alpha (FRα) expression.

This description comes directly from the study's public registry record.

Talk to the study team

ABBVIE CALL CENTER  ·  844-663-3742  ·  abbvieclinicaltrials@abbvie.com

Always discuss trial participation with your own doctor first.

Locations (40)

University of California Los Angeles /ID# 269339Los Angeles, California, United StatesRecruiting
Norton Cancer Institute - St. Matthews /ID# 269070Louisville, Kentucky, United StatesCompleted
Holy Cross Hospital - Silver Spring /ID# 269344Silver Spring, Maryland, United StatesRecruiting
Mercy David C. Pratt Cancer Center /ID# 269350St Louis, Missouri, United StatesRecruiting
The Center Of Hope /ID# 269348Reno, Nevada, United StatesActive Not Recruiting
Holy Name Medical Center /ID# 269340Teaneck, New Jersey, United StatesRecruiting
New York Oncology Hematology - Albany Cancer Center /ID# 269345Albany, New York, United StatesCompleted
Women'S Cancer Care Associates /ID# 269980Albany, New York, United StatesCompleted
Duke Cancer Institute /ID# 269342Durham, North Carolina, United StatesRecruiting
Summa Health /ID# 269349Akron, Ohio, United StatesRecruiting
UT Southwestern Medical Center /ID# 269341Dallas, Texas, United StatesRecruiting
Memorial Hermann Southeast Hospital /ID# 269347Houston, Texas, United StatesCompleted

+ 28 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06365853