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Study identifier: NCT06364917 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

DISCERN: Dual Versus Single ICB in PDL-1 Negative NSCLC

Condition: Non Small Cell Lung Cancer  ·  Sponsor: University of Alabama at Birmingham

PhasePhase 2
Planned participants24
Who can joinAll sexes, 18 Years to 89 Years
Healthy volunteersNo

About this study

The purpose of this study, known as DISCERN, is to compare two different treatments for a type of lung cancer called non-small cell lung cancer (NSCLC) that does not show a marker known as PD-L1. This study will help us understand if using two types of immune therapy together with chemotherapy is better than using one type of immune therapy with chemotherapy. We're doing this by looking at changes in the subject's cancer's DNA in the blood after starting treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Aakash Desai, MD, MPH  ·  (205) 934-3411  ·  aakashdesai@uabmc.edu

Margaret Thomas, MPH  ·  margaretannthomas@uabmc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Alabama at BirminghamBirmingham, Alabama, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06364917