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Study identifier: NCT06364371 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Dynamic Multi-omics Integration Model to Predict Neoadjuvant Therapy Response in Locally Advanced Rectal Cancer

Condition: Predictive Cancer Model · Pathologic Complete Response  ·  Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University

PhaseN/A
Planned participants106
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

The goal of this observational study is to establish a dynamic multi-omics integration model for predicting pathological complete response (pCR) after neoadjuvant treatment in locally advanced (T3-4NxM0) rectal cancer, providing support for subsequent patient selection for the watch-and-wait strategy. The main question it aims to answer is: What is the predictive value of this model to assess individual achievement of pathological complete response (pCR) after neoadjuvant treatment? Eligible patients will be prospectively enrolled, and the clinical features of their pre-neoadjuvant treatment, during-treatment, and post-treatment preoperative will be collected and annotated.

This description comes directly from the study's public registry record.

Talk to the study team

Jun Huang  ·  +86-13926451242  ·  huangj97@mail.sysu.edu.cn

Meijin Huang  ·  +86-13924073322  ·  meijinhuang3@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

The Sixth Affiliated Hospital, Sun Yatsen UniversityGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06364371