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Study identifier: NCT06364176 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Targeting Inflammation With Losartan to Improve Response to Modulator Therapy in Cystic Fibrosis.

Condition: Cystic Fibrosis  ·  Sponsor: University of Kansas Medical Center

PhasePhase 2
Planned participants42
Who can joinAll sexes, 12 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to test use of losartan in those with cystic fibrosis (CF) on modulator therapy. The main question it aims to answer is if treatment with losartan improves response of the CF transmembrane conductance regulator (CFTR) channel to modulator therapy. Participants will be asked take losartan or placebo for twelve weeks and will have changes in sweat chloride levels measured as a marker of CFTR function.

This description comes directly from the study's public registry record.

Talk to the study team

Heidi Hellwig  ·  9135886045  ·  hhellwig@kumc.edu

Carolina Aguiar  ·  9139459295  ·  caguiar@kumc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Kansas Medical CenterKansas City, Kansas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06364176