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Study identifier: NCT06362980 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study With BPI-1178 and Osimertinib in Advanced Non-small Cell Lung Cancer Patients With EGFR Mutations

Condition: NSCLC  ·  Sponsor: National Cancer Center, China

PhasePhase 1
Planned participants20
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

BPI-1178 is a novel, orally administered inhibitor of both cyclin-dependent kinase 4 (CDK4) and CDK6 kinase activity. This open-label investigator-initiated trial (IIT) phase I study was designed to evaluate the safety and efficacy of oral BPI-1178 in combination with osimertinib in patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) and epidermal growth factor receptor (EGFR) Mutations.

This description comes directly from the study's public registry record.

Talk to the study team

Puyuan Xing, Doctorate  ·  +86-10-87787421  ·  xingpuyuan@cicams.ac.cn

Always discuss trial participation with your own doctor first.

Locations (1)

National Cancer CenterBeijing, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06362980