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Study identifier: NCT06362369 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

Condition: Advanced Cancer · Advanced Solid Tumor · Melanoma  ·  Sponsor: 7 Hills Pharma, LLC

PhasePhase 1/Phase 2
Planned participants126
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is an open-label Phase Ib (Part A) dose escalation followed by a blinded, randomized, multi cohort Phase 2a (Part B) comparison of combination vs. reference regimens. Currently study will only be enrolling the Phase 1b and the Phase 2a protocol requirements will be added to the study near completion of the Phase 1b

This description comes directly from the study's public registry record.

Talk to the study team

Sr. Director Clinical Affairs  ·  1.210.279.1998  ·  nicole@7hillspharma.com

VP Clinical Affairs and Regulatory  ·  6892623575  ·  bill@7hillspharma.com

Always discuss trial participation with your own doctor first.

Locations (5)

University of Colorado Cancer CenterAurora, Colorado, United StatesRecruiting
Florida Cancer SpecialistsLake Mary, Florida, United StatesCompleted
Dartmouth HitchcockLebanon, New Hampshire, United StatesRecruiting
Brown University Health Cancer InstituteProvidence, Rhode Island, United StatesRecruiting
MD Anderson Cancer CenterHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06362369