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Study identifier: NCT06361784 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Improving the Success Rate for Thoracic Radiotherapy Through Specific Cardiac Substructure Dosimetry: Location Matters. (LOCATION MATTERS)

Condition: Locally Advanced Lung Non-Small Cell Carcinoma  ·  Sponsor: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

PhaseN/A
Planned participants150
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

The prospective study LOCATION MATTERS aims to investigate the radiation-induced damage to the heart and the cardiovascular system in patients treated with thoracic radiotherapy. Patients enrolled in the study will complete a set of extensive measures at the baseline, end of RT, and 9 months after treatment. Ultrasound exams, CT scans, pulmonary tests and wearable devices will assess functional and morphological parameters and the association with their variation and the dose delivered to the heart substructures and to the normal lung.

This description comes directly from the study's public registry record.

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Locations (1)

Fondazione IRCCS Istituto Nazionale dei TumoriMilan, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06361784