Condition: Colitis, Ulcerative · Sleep Quality · Gastrointestinal Microbiome · Sponsor: Xijing Hospital
Ulcerative colitis(UC) is one of the two main forms of inflammatory bowel disease(IBD), which seriously affects the quality of life of patients. Previous studies have demonstrated that more than 60% of IBD patients have sleep disorders, which is emerging as an important risk factor for disease recurrence and poor prognosis. However, the mechanisms by which sleep disorders regulates the occurrence and development of IBD remain undefined. This study aims to explore the clinical characteristics of ulcerative colitis patients with sleep disorders based on the microbiota-gut-brain axis, to analyze the effects of sleep disorders on autonomic nervous function, gut microbiota, and metabolites in UC patients.
This description comes directly from the study's public registry record.
Jiaming Zhou · +86 173 9207 9496 · 1041181972@qq.com
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| Xijing Hospital | Xi'an, Shaanxi, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06359808