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Study identifier: NCT06357845 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Linking Somatic Mutation Rate With Baseline Exposure in East Palestine

Condition: Somatic Mutation  ·  Sponsor: Case Comprehensive Cancer Center

PhaseNA
Planned participants500
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

The goal of this study is to This research team is conducting this study to develop methods to measure the biological impact of exposure to the chemicals released following the February 3, 2023 train derailment on residents of East Palestine, Ohio, and surrounding communities. The main question it aims to answer is: * What biological impact will be measured based on DNA damage? * In participants who provide a biospecimen, how are biomarker changes related to proximity to the derailment and variations in residents' health histories and behaviors? Participants will: * Complete a brief survey asking about experiences related to the February 3, 2023 train derailment, health experiences, and concerns following the derailment, and background information regarding health history. * Possibly contribute biospecimens such as blood, spit, hair, and/or toenail clippings. * Receive communication about study updates and future research opportunities. * A total of 40 study participants will be recruited to participate in a 90-minute interview. The interviews will be video and audio recorded.

This description comes directly from the study's public registry record.

Talk to the study team

Fredrick R Schumacher, PhD  ·  216-368-0351  ·  healthyfutures@case.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Case Western Reserve University, Case Comprehensive Cancer CenterCleveland, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06357845