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Study identifier: NCT06354231 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

DV Combined With Toripalimab for Renal Preservation in Solitary Kidney or Renal Insufficiency or Bilateral Multiple UTUC

Condition: Renal Insufficiency · Upper Urinary Tract Urothelial Carcinoma · Solitary Kidney  ·  Sponsor: Fudan University

PhasePhase 2
Planned participants20
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Approximately 20 participants will be enrolled in the study to evaluate the efficacy and safety of the combination of DV (DV, 2.0 mg/kg, intravenously administered every 2 weeks) and toripalimab (toripalimab, 3.0mg/kg, intravenously administered every 2 weeks). Subjects will receive 6 cycles of DV and toripalimab, followed by laser surgery to remove ureteral or renal pelvis tumors, followed by 12 cycles of DV and 1 year of toripalimab consolidation therapy. Efficacy and safety were evaluated by cystoscopy, ureteroscopy, laboratory tests, and imaging examinations after treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Dingwei Ye, Doctor  ·  64175590-82800  ·  dwyeli@163.com

Hailiang Zhang, Doctor  ·  64175590-82800  ·  zhanghl918@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

Fudan University Shanghai Cancer CenterShanghai, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06354231