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Study identifier: NCT06351657 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Personalized Monitoring of Non-foveal, Non-vision Compromising Atrophic Age-related Macular Degeneration With Artificial Intelligence and Identification of Disease Progression

Condition: Age-Related Macular Degeneration · Geographic Atrophy  ·  Sponsor: Medical University of Vienna

PhaseN/A
Planned participants200
Who can joinAll sexes, 55 Years to 99 Years
Healthy volunteersNo

About this study

The goal of this prospective, multinational, multicenter observational study is to assess and predict progression in non-foveal, non-vision compromising atrophic AMD on an individual-based level over two years. The main objectives of this study are: * Assess the individual progression rate of a patient in non-foveal, non-vision compromising atrophic AMD and assess personalized risk of progression based on imaging. * Identify and quantify focal and global alterations in the retina in regard to disease progression. * Evaluate the monitoring of AMD progression using approved AI algorithms. All patients will be followed for 24 months with 6 month intervals to assess clinical changes. Monitoring of disease progression will be performed using the following routine in-vivo imaging procedures: * Scanning Laser Fundus Photography * Color Fundus Photography (CFP) * Optical Coherence Tomography (OCT) * Optical Coherence Tomography Angiography (OCTA) Patients will be asked for their medical history. Standard ophthalmic examination, as well as a questionnaire on visual function will be carried out. No intervention will be performed during the study since no treatment is yet available within Europe. As soon as treatment is approved in the EU, patients in this cohort might receive treatment according to availability in their respective country and standard of care. If treatment will be performed, it will be as standard of care outside the study according to each country's standard of c…

This description comes directly from the study's public registry record.

Talk to the study team

Gregor Reiter, Priv.-Doz. Ing. DDr., BA MSc  ·  +43 1 40400-73419  ·  gregor.reiter@meduniwien.ac.at

Always discuss trial participation with your own doctor first.

Locations (7)

Medical University of ViennaVienna, AustriaNot Yet Recruiting
CHU DijonDijon, FranceRecruiting
University Medical Center LjubljanaLjubljana, SloveniaRecruiting
Fundacio de Recerca Clinic Barcelona-Institut D Investigacions BiomedBarcelona, SpainRecruiting
Vista Klinik BinningenBinningen, SwitzerlandRecruiting
University of ZürichZurich, SwitzerlandRecruiting
Queen's Unviversity BelfastBelfast, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT06351657