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Study identifier: NCT06351124 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Beta-Hydroxybutyrate Feasibility Treating IBD

Condition: Crohn's Disease · Inflammatory Bowel Diseases  ·  Sponsor: University of Texas at Austin

PhasePhase 1/Phase 2
Planned participants20
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This clinical trial aims to understand the feasibility of patients taking ketone body supplement beta-hydroxybutyrate (BHB) for 4 weeks with a confirmed diagnosis of Crohn's disease and starting new therapy for active disease. The main questions it aims to answer are: * BHB supplementation will be feasible and acceptable to patients. * BHB supplementation will be associated with a reduction in systemic inflammation. * BHB supplementation will be associated with a reduction in pro-inflammatory bacterial colonies. Participants will: * Take 3 capsules x 3 times per day for 4 weeks. * Document food consumption using a 24-hour food recall questionnaire. * Provide blood and fecal samples twice, at the beginning of the study and the 4-week mark. Researchers will compare the group taking the ketone body supplement and the group not taking the supplement to see if the supplement provides relief of symptoms suffered from Crohn's disease.

This description comes directly from the study's public registry record.

Talk to the study team

Linda A. Feagins, Associate Professor, MD  ·  512-495-5641  ·  linda.feagins@austin.utexas.edu

Juan P Robayo, Research Program Manager, MPH  ·  407-928-3556  ·  juan.robayo@austin.utexas.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Texas at AustinAustin, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06351124