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Study identifier: NCT06350110 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Fourth-gen CAR T Cells Targeting BCMA/CD19 for Refractory Systemic Lupus Erythematosus (SLE)

Condition: Systemic Lupus Erythematosus · Lupus Nephritis · Autoimmune Diseases  ·  Sponsor: Essen Biotech

PhasePhase 1/Phase 2
Planned participants75
Who can joinAll sexes, 18 Years to 90 Years
Healthy volunteersNo

About this study

This study is a preliminary investigation, with a single-group design, not randomized and transparent, focusing on treatment. Its purpose is to identify the highest dose of BH002 injection (CD19-BCMA CAR-T cells) that patients suffering from resistant systemic lupus erythematosus can tolerate.

This description comes directly from the study's public registry record.

Talk to the study team

Rhoda M Smith, Phd  ·  +12077706670  ·  clinical-trials@essen-biotech.com

Always discuss trial participation with your own doctor first.

Locations (1)

District One HospitalBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06350110