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Study identifier: NCT06349980 Synced from ClinicalTrials.gov · July 29, 2026
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A Study to Explore the Reasonable Dosage and Evaluate the Efficacy, Safety and Tolerability of HLX10 and HLX04 with or Without HLX53 in Untreated, Locally Advanced or Metastatic Hepatocellular Carcinoma Patients.

Condition: Carcinoma, Hepatocellular  ·  Sponsor: Shanghai Henlius Biotech

PhasePhase 2
Planned participants117
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The study is being conducted to to explore the reasonable dosage and evaluate the efficacy, safety and tolerability of Serplulimab Injection (HLX10, a Recombinant Anti-PD-1 Antibody) and HLX04 (a Biosimilar to Bevacizumab) With or Without HLX53 (an Anti-TIGIT Fc Fusion Protein) in Untreated, Locally Advanced or Metastatic Hepatocellular Carcinoma Patients.

This description comes directly from the study's public registry record.

Talk to the study team

Jia Fan, Dr  ·  021-64041990  ·  fan.jia@zs-hospital.sh.cn

Huichuan Sun, Dr  ·  sun.huichuan@zs-hospital.sh.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Zhongshan Hospital, Fudan UniversityShanghai, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06349980