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Study identifier: NCT06345339 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

Condition: Hypothyroidism  ·  Sponsor: AbbVie

PhasePhase 2/Phase 3
Planned participants2800
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This study will evaluate the efficacy and safety of Armour Thyroid treatment compared with synthetic T4 in subjects who have primary hypothyroidism and are currently stabilized (i.e., in-range thyroid-stimulating hormone \[TSH\]) on synthetic T4 treatment. This study will also therefore evaluate the efficacy and safety of dose conversion from synthetic T4 therapy to Armour Thyroid therapy.

This description comes directly from the study's public registry record.

Talk to the study team

ABBVIE CALL CENTER  ·  844-663-3742  ·  abbvieclinicaltrials@abbvie.com

Always discuss trial participation with your own doctor first.

Locations (139)

Central Research Associates /ID# 255719Birmingham, Alabama, United StatesRecruiting
UAB Hospital /ID# 262565Birmingham, Alabama, United StatesRecruiting
Kaiser San Diego Dept Endocrinology, SCPMG /ID# 262552Bonita, California, United StatesRecruiting
Facey Medical Foundation - Burbank /ID# 262104Burbank, California, United StatesRecruiting
John Muir Medical Center /ID# 257103Concord, California, United StatesRecruiting
Diagnamics Inc. /ID# 262680Encinitas, California, United StatesRecruiting
Providence - St. Jude Medical Center /ID# 256520Fullerton, California, United StatesRecruiting
NorCal Medical Research /ID# 256512Greenbrae, California, United StatesRecruiting
Velocity Clinical Research - Huntington Park /ID# 259044Huntington Park, California, United StatesRecruiting
Scripps Whittier Diabetes Institute /ID# 259215La Jolla, California, United StatesRecruiting
Facey Medical Foundation /ID# 260863Mission Hills, California, United StatesRecruiting
Hoag Memorial Hospital Presbyterian /ID# 260990Newport Beach, California, United StatesRecruiting

+ 127 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06345339