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Study identifier: NCT06342414 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer

Condition: Hepatocellular Carcinoma · Intrahepatic Cholangiocarcinoma · Cholangiocarcinoma  ·  Sponsor: City of Hope Medical Center

PhaseN/A
Planned participants400
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

It is sometimes difficult to precisely understand whether a primary liver cancer is a hepatocellular carcinoma or a cholangiocarcinoma. The researchers will develop and validate a liquid biopsy, based on exosomal content analysis and powered by machine learning, to help clinicians differentiate these two cancers before surgery.

This description comes directly from the study's public registry record.

Talk to the study team

Ajay Goel, PhD  ·  6262183452  ·  AJGOEL@COH.ORG

Always discuss trial participation with your own doctor first.

Locations (5)

City of Hope Medical CenterDuarte, California, United StatesRecruiting
Graduate School of Medical Sciences, Kyushu UniversityFukuoka, JapanRecruiting
Graduate School of Medical Sciences, Kumamoto UniversityKumamoto, JapanRecruiting
Hokkaido University Graduate School of MedicineSapporo, JapanRecruiting
Tokushima UniversityTokushima, JapanRecruiting

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Source record: clinicaltrials.gov/study/NCT06342414