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Study identifier: NCT06340230 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

SHR-A1811 Alone or in Combination With Adebrelimab as Neoadjuvant Treatment in HR Positive/HER2 Low Breast Cancer

Condition: HR Positive/HER2 Low Breast Cancer  ·  Sponsor: Shengjing Hospital

PhasePhase 2
Planned participants93
Who can joinFemale, 18 Years to 75 Years
Healthy volunteersNo

About this study

This is an open-label, phase II study evaluating the efficacy and safety of SHR-A1811 alone or in combination with Adebrelimab in Stage II-III HR Positive/HER2 Low Breast Cancer. Subjects will receive the neoadjuvant therapy of SHR-A1811 alone or in combination with Adebrelimab for six cycles, and then undergo surgery within 4 weeks after neoadjuvant therapy. Efficacy will be assessed every 2 cycles.

This description comes directly from the study's public registry record.

Talk to the study team

Nan Niu, MD  ·  86-18940256668  ·  niunannancy@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

Shengjing Hospital affiliated to China Medical UniversityShenyang, Liaoning, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06340230