Condition: Parkinson Disease · Sponsor: Casa di Cura San Raffaele Cassino
This is a prospective, observational, cohort pilot study of standardize volume of aerobic exercise on changes in BDNF concentration at 4-weeks of exercise training among Parkinson disease patients. Thirty (N=30) participants will be consecutively enrolled and assigned to 2 groups: 1) Extensive Rehabilitation Group (exercise volume: 180 METs-min/week) or 2) Intensive Rehabilitation Group (exercise volume: 1350 METs-min/week). The primary objective is to evaluate the dose-response effects of two different rehabilitation settings, characterized by different workload (measured as energy expenditure), on blood BDNF levels.
This description comes directly from the study's public registry record.
Maria Francesca De Pandis, MD, PhD · 0039 0776394740 · maria.depandis@sanraffaele.it
Maria Gaglione · maria.gaglione@sanraffaele.it
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| San Raffaele Cassino | Cassino, Frosinone, Italy | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06339398