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Study identifier: NCT06339190 Synced from ClinicalTrials.gov · July 29, 2026
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Neurofilament Light Chain And Voice Acoustic Analyses In Dementia Diagnosis

Condition: Neurodegenerative Diseases · Dementia  ·  Sponsor: Monash University

PhaseN/A
Planned participants1000
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

This cohort study aims to determine if a blood test can aid with diagnosing dementia in anyone presenting with cognitive complaints to a single healthcare network. The investigators will measure levels of a brain protein, Neurofilament light chain (Nfl), and assess changes in language using speech tests. Participants will have a single blood test and speech test, and will be followed up at 12-months to complete questionnaires and cognitive scales over the phone. The speech test will also be completed again at 12-months. Individuals at risk of a Fronto-temporal dementia syndrome will be eligible to complete optional genetic testing involving an 'at home' saliva sample.

This description comes directly from the study's public registry record.

Talk to the study team

Prof. Amy Brodtmann, MBBS, FRACP, PhD, FANZAN  ·  03 9094 9540  ·  amy.brodtmann@monash.edu

Svetlana Ivanic, BSc(Hons)  ·  svetlana.ivanic@monash.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Box Hill HospitalBox Hill, Victoria, AustraliaRecruiting
Wantirna HealthWantirna, Victoria, AustraliaRecruiting

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Source record: clinicaltrials.gov/study/NCT06339190