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Study identifier: NCT06337864 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effect of Large Neutral Amino Acids in Adults With Classical Phenylketonuria

Condition: Brain Diseases · Brain Diseases, Metabolic · Brain Diseases, Metabolic, Inborn  ·  Sponsor: Rigshospitalet, Denmark

PhaseNA
Planned participants30
Who can joinAll sexes, 18 Years to 50 Years
Healthy volunteersYes

About this study

The overall aim of this study is to evaluate LNAA treatment as a potential alternative to conventional dietary treatment for PKU. This study investigates the effects of LNAA treatment compared to the classic dietary treatment on cerebral dopamine synthesis in patients with classic PKU. We will assess LNAAs effectiveness on neurotransmitter synthesis, cognitive function, mental health, and safety, compared to the standard diet.

This description comes directly from the study's public registry record.

Talk to the study team

Allan Lund, Professor, MD, DMSc  ·  +4535451303  ·  allan.lund@regionh.dk

Olivia Fjellbirkeland, MD  ·  olivia.welle.fjellbirkeland@regionh.dk

Always discuss trial participation with your own doctor first.

Locations (2)

Center for Inherited Metabolic DiseasesCopenhagen, DenmarkRecruiting
Copenhagen University Hospital, RigshospitaletCopenhagen, DenmarkNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06337864