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Study identifier: NCT06336733 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Randomized Controlled Trial in Patients on Long-term Colchicine With Colchicine-resistant Familial Mediterranean Fever (FMF) to Evaluate the Efficacy of On-demand Anakinra Treatment for Painful Attacks in Patients Who Refuse Continuous Daily Therapy

Condition: FMF  ·  Sponsor: Assistance Publique - Hôpitaux de Paris

PhasePhase 3
Planned participants50
Who can joinAll sexes, 6 Years to no upper limit
Healthy volunteersNo

About this study

To evaluate the efficacy on clinical symptoms in case of FMF attack among FMF patients resistant to Colchicine of * on demand anakinra treatment (100 mg/d from the prodromal phase of the attack until 24 hours of remission (during 7 days maximum) associated with daily colchicine. * compared to analgesic associated with daily colchicine in patients refusing continuous anti-IL-1 treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Léa SAVEY  ·  0033 1 56 01 67 91  ·  lea.savey@aphp.fr

Sophie Georgin-Lavialle, MD,PHD  ·  00 33 1 56 01 74 31  ·  sophie.georgin-lavialle@aphp.fr

Always discuss trial participation with your own doctor first.

Locations (1)

Service de Médecine interne Hopital TenonParis, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT06336733