Condition: Colorectal Cancer Prevention · Sponsor: Odense University Hospital
The goal of this prospective randomized double-blinded bi-national study is to test the prophylactic effect of polyacetylenes from carrots on the population of patients who had a resection of high-risk adenomas of the large bowel. The main question it aims to answer is: Will carrot juice rich in polyacetylenes inhibit neoplastic transformation and growth in high-risk humans? Participants will have to drink 100 ml of juice daily after the adenoma resection for 1 year and keep a simple diary/calendar. Researchers will compare the group with ingestion of Falcarinol (FaOH) / Falcarindiol (FaDOH) rich carrot juice versus the group consuming placebo juice, to see if the polyacetylenes significantly reduces neoplastic transformation and growth in high-risk patients.
This description comes directly from the study's public registry record.
Gunnar Baatrup, Professor · +4520575154 · Gunnar.Baatrup@rsyd.dk
Alexandra D Agache, Postdoc · +4520355717 · Alexandra.Agache@rsyd.dk
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| Department of Surgery, Odense University Hospital | Odense, Denmark | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06335420