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Study identifier: NCT06335407 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effect of Sublingual Formulation of Dexmedetomidine Hydrochloride (HCl) (BXCL501) - Outpatient Study

Condition: Alcohol Use Disorder (AUD) · Post Traumatic Stress Disorder (PTSD)  ·  Sponsor: Pharmacotherapies for Alcohol and Substance Use Disorders Alliance

PhasePhase 1
Planned participants10
Who can joinAll sexes, 21 Years to 65 Years
Healthy volunteersNo

About this study

The overall objective of the proposed study is to determine if Dexmedetomidine HCl (BXCL501) is safe for treatment of alcohol use disorder (AUD) with comorbid posttraumatic stress disorder (PTSD) in an outpatient setting and also shows potential signals of efficacy thereby supporting the conduct of later phase clinical trials.

This description comes directly from the study's public registry record.

Talk to the study team

Ismene Petrakis, MD  ·  (203) 932-5711  ·  ismene.petrakis@yale.edu

Jenelle Newcomb, BA  ·  (203) 932-5711  ·  jenelle.leblanc@yale.edu

Always discuss trial participation with your own doctor first.

Locations (1)

VA Connecticut Healthcare SystemWest Haven, Connecticut, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06335407