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Study identifier: NCT06334952 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Efficacy of Personnalized Transcranial Direct Current Electrical Stimulation (tDCS) in Drug-resistant Epileptic

Condition: Epilepsy · Drug Resistant Epilepsy  ·  Sponsor: Assistance Publique Hopitaux De Marseille

PhaseNA
Planned participants60
Who can joinAll sexes, 9 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to to obtain a significant decrease in seizure frequency in patients with refractory focal epilepsy after applying treatment of cathodal tDCS, compared to sham stimulation drug-resistant epileptic patient. The main questions it aims to answer are: * Changes in quality of life * Percent of newly reported side effects after the stimulation period * Scores in epilepsy severity. Participants will be randomized in a cross-over, and will receive 10 days of tDCS or Sham. Each day will allow 2 periods of 20 minutes stimulation separated by 20 minutes off (with 40 minutes of cathodal stimulation total).

This description comes directly from the study's public registry record.

Talk to the study team

Fabrice Bartolomei, MD, PhD  ·  0491384990  ·  fabrice.bartolomei@ap-hpm.fr

Sophie Tardoski  ·  0491381594  ·  sophie.tardoski@ap-hm.fr

Always discuss trial participation with your own doctor first.

Locations (7)

Service de Neurophysiologie Clinique de l'Enfant et de L'Adulte, Pôle de Neurosciences CliniquesBordeaux, FranceRecruiting
Département Neurologie Fonctionnelle et Epilepsie, Hôpital neurologique - Hospices Civils de LyonBron, FranceRecruiting
Service de Neurophysiologie clinique - Hôpital Roger Salengro, CHU LilleLille, FranceNot Yet Recruiting
Service Epileptologie et Rythmologie Cérébrale, Hôpital La TimoneMarseille, FranceRecruiting
Service de Neurophysiologie clinique - GHU Psychiatrie et Neurosciences Sainte-AnneParis, FranceNot Yet Recruiting
Service de Neurologie - CHU de Rennes - Hôpital PontchaillouRennes, FranceNot Yet Recruiting
Explorations neurophysiologiques - Pôle neurosciences, CHU de Toulouse, Hôpital Pierre Paul RiquetToulouse, FranceNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06334952