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Study identifier: NCT06334575 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Molecular Signatures Associated With Response to ICS Treatment in Patients With COPD Stratified by Eosinophil Levels

Condition: Chronic Obstructive Pulmonary Disease  ·  Sponsor: Maria Joyera Rodríguez

PhasePhase 4
Planned participants135
Who can joinAll sexes, 40 Years to no upper limit
Healthy volunteersNo

About this study

The 3TR-ICS COPD study is an international, multicentre, randomized, parallel, controlled study that will recruit clinically stable former smokers COPD patients (with no exacerbations in the previous 8 weeks) on treatment with dual long-acting bronchodilators (LABA+LAMA), minimum 8 weeks of usage, not receiving ICS (either naïve or \> 3 months since last usage). The overall objective of this clinical trial is to identify the molecular signatures associated with the molecular response to ICS treatment in patients with COPD stratified by the levels of circulating eosinophils, and the potential influence of the pulmonary microbiome

This description comes directly from the study's public registry record.

Talk to the study team

Rosa Faner  ·  +34932775400  ·  rfaner@recerca.clinic.cat

Maria Joyera  ·  joyera@recerca.clinic.cat

Always discuss trial participation with your own doctor first.

Locations (6)

Philips University of MarburgMarburg, GermanyRecruiting
Academisch Ziekenhuis GroningenGroningen, NetherlandsRecruiting
Clínic BarcelonaBarcelona, SpainRecruiting
Son EspasesPalma de Mallorca, SpainRecruiting
University of LeicesterLeicester, United KingdomNot Yet Recruiting
Imperial College LondonLondon, United KingdomNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06334575