Condition: Non-small Cell Lung Cancer(NSCLC) · Head and Neck Squamous Cell Carcinoma(HNSCC) · Renal Cell Carcinoma(RCC) · Sponsor: LG Chem
This is a Phase 1a/1b, first-in-human (FIH), multi-center, open-label, non-randomized, dose escalation study, designed to determine the Maximum tolerated dose(MTD)/Recommended Phase 2 dose (RP2D) and to evaluate safety, tolerability, preliminary efficacy, pharmacokinetics, immunogenicity, pharmacodynamics of LB-LR1109 as monotherapy in participants with advanced and/or metastatic non small cell lung cancer (NSCLC), head and neck squamous cell carcinoma (HNSCC), renal cell carcinoma (RCC), urothelial carcinoma, or malignant melanoma and no available standard of care treatment options, and as combination therapy with atezolizumab in participants with advanced and/or metastatic NSCLC.
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| NEXT Oncology | Fairfax, Virginia, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06332755