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Study identifier: NCT06331364 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

TREATment of Lower Respiratory Tract Infection in Selected Hospitals in Southern Sri Lanka (TREAT-SL): a Stepped-Wedge Cluster Randomized Trial

Condition: Lower Resp Tract Infection  ·  Sponsor: Duke University

PhaseNA
Planned participants765
Who can joinAll sexes, 14 Years to no upper limit
Healthy volunteersNo

About this study

This is a stepped-wedge, cluster-randomized, two-arm, open-label, clinical trial of an electronic clinical decision support tool (eCDST) for the diagnosis and treatment of lower respiratory tract infection (LRTI) among patients at three sites in Southern Province, Sri Lanka. The primary objective of this trial is to determine the impact of an electronic clinical decision support tool (eCDST) on clinical outcomes and antibacterial prescription in subjects with LRTI in the intervention group compared to the control group. The study will enroll 765 patients ≥ 14 years of age. Medical wards will be randomized in clusters to the intervention at intervals of 3-6 months until all clusters cross over. Participants will be followed for 30 days from enrollment to record clinical outcomes and any antimicrobials prescribed (a maximum of 14 days).

This description comes directly from the study's public registry record.

Talk to the study team

Gayani Tillekeratne, MD, MSc  ·  (919) 681-7760  ·  gayani.tillekeratne@duke.edu

Stefany Olague, MPH  ·  (919)668-8131  ·  stefany.olague@duke.edu

Always discuss trial participation with your own doctor first.

Locations (3)

Base Hospital BalapitiyaBalapitiya, Sri LankaRecruiting
Galle National HospitalKarapitiya, Sri LankaRecruiting
District General Hospital MataraMatara, Sri LankaRecruiting

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Source record: clinicaltrials.gov/study/NCT06331364