Condition: Kidney Stone · Kidney Calculi · Urolithiasis · Sponsor: University of Alabama at Birmingham
The goal of this trial is to test if colonization with the gut bacteria Oxalobacter formigenes leads to a reduction in urinary oxalate excretion in patients with calcium oxalate kidney stone disease. The study will recruit adult participants with a history of calcium oxalate kidney stones who are not colonized with Oxalobacter formigenes. Participants will * ingest fixed diets containing low and moderately high amounts of oxalate for 4 days at a time * collect urine, blood and stool samples during the fixed diets * ingest a preparation of live Oxalobacter formigenes to induce colonization with Oxalobacter formigenes
This description comes directly from the study's public registry record.
Sonia Fargue, PhD · 2059756932 · sfargue@uab.edu
Demond Wiley · 2059345712 · kidneystone@uabmc.edu
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| University of Alabama at Birmingham | Birmingham, Alabama, United States | Recruiting |
| UTSW | Dallas, Texas, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06330246