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Study identifier: NCT06328361 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Nordic ORgan Preservation Pilot Approach Nonrandomised Single-Arm Trial for Non-Operative Management of Rectal Cancer

Condition: Rectal Cancer · Rectal Adenocarcinoma  ·  Sponsor: Tampere University Hospital

PhaseNA
Planned participants200
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this one-arm clinical trial is to implement and study the oncological outcomes of nonoperative management of rectal cancer having complete clinical response to neoadjuvant therapy. The main questions to answer are * if the oncological results of nonoperative management after Nordic practice in chemoradiotherapy indications differ from experiences elsewhere * what is the organ preservation rate * what is the local regrowth rate

This description comes directly from the study's public registry record.

Talk to the study team

Toni T Seppälä, MD, PhD  ·  +358444722846  ·  toni.seppala@tuni.fi

Always discuss trial participation with your own doctor first.

Locations (13)

East Tallinn Central HospitalTallinn, EstoniaRecruiting
North Estonia Medical CentreTallinn, EstoniaRecruiting
West Tallinn Central HospitalTallinn, EstoniaRecruiting
Tartu University HospitalTartu, EstoniaRecruiting
Helsinki University Central HospitalHelsinki, FinlandRecruiting
Jyväskylä Central HospitalJyväskylä, FinlandRecruiting
Kuopio University HospitalKuopio, FinlandRecruiting
Oulu University HospitalOulu, FinlandRecruiting
Satakunta Central HospitalPori, FinlandRecruiting
Seinajoki Central HospitalSeinäjoki, FinlandRecruiting
Tampere University HospitalTampere, FinlandRecruiting
Turku University HospitalTurku, FinlandRecruiting

+ 1 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06328361