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Study identifier: NCT06327568 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Anal Cancer and/or Precancer Screening: Performance Analysis of the BD Onclarity™ HPV Assay on Anal Specimens

Condition: Anal Intraepithelial Neoplasia 2 · Anal Intraepithelial Neoplasia 1 · Anal Cancer  ·  Sponsor: European Institute of Oncology

PhaseN/A
Planned participants200
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Human papillomavirus (HPV) infection has been implicated as a necessary cause for the development of the majority of anogenital neoplasms which represent approximately 95% of anal tumors. Persistent high risk HR-HPV infection promotes progression from intraepithelial lesions high-grade squamous anal tumors (AIN) (H-SIL) to invasive anal tumors. The diagnosis of AIN is made by cytology or biopsy during routine examinations. To date, no HPV test has been clinically validated for anal specimens and none are available in the molecular diagnostics market for this purpose. The performance analysis of an HPV Test with simultaneous genotyping on anal samples could implement anal cancer screening without an invasive procedure and with one simple approach.

This description comes directly from the study's public registry record.

Talk to the study team

Fabio Bottari  ·  +390294372716  ·  fabio.bottari@ieo.it

Cristina Mazzon  ·  cristina.mazzon@ieo.it

Always discuss trial participation with your own doctor first.

Locations (1)

European Institute of OncologyMilan, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06327568