Condition: Oncology · MEK Mutation · RAF Gene Mutation · Sponsor: Nested Therapeutics, Inc
This is a two-part Phase 1, open label, multi-center, single arm, non-randomized, multiple dose, safety, pharmacokinetic (PK) and preliminary efficacy study of single agent NST-628 in adult patients with MAPK pathway mutated/dependent advanced solid tumors who have exhausted standard treatment options.
This description comes directly from the study's public registry record.
CMO · 617-468-4292 · info@nestedtx.com
Ann Marie Kennedy · 919-427-4225 · amkennedy@nestedtx.com
Always discuss trial participation with your own doctor first.
| UCSF Helen Diller Family Comprehensive Cancer Center | San Francisco, California, United States | Recruiting |
| UCLA Hematology/Oncology | Westwood, Los Angeles, California, United States | Recruiting |
| Sarah Cannon Research Institute at Health ONE | Denver, Colorado, United States | Recruiting |
| Yale Cancer Center | New Haven, Connecticut, United States | Completed |
| Moffitt Cancer Center | Tampa, Florida, United States | Recruiting |
| Roswell Park | Buffalo, New York, United States | Recruiting |
| Laura & Isaac Perlmutter Cancer Center at NYU Langone Health | New York, New York, United States | Recruiting |
| Columbia University Medical Center | New York, New York, United States | Recruiting |
| Memorial Slone Kettering Cancer Center | New York, New York, United States | Recruiting |
| UPMC Hillman Cancer Center | Pittsburgh, Pennsylvania, United States | Recruiting |
| SCRI Oncology Partners | Nashville, Tennessee, United States | Recruiting |
| Vanderbilt-Ingram Cancer Center | Nashville, Tennessee, United States | Recruiting |
+ 11 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06326411