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Study identifier: NCT06324318 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Parenting in 2 Worlds Multisite Trial

Condition: Parenting · Mental Health Wellness 1 · Substance Use  ·  Sponsor: Arizona State University

PhasePhase 2
Planned participants1440
Who can joinAll sexes, 12 Years to no upper limit
Healthy volunteersYes

About this study

This research study will test the effectiveness of a culturally grounded parenting intervention called Parenting in 2 Worlds (P2W). This intervention is designed for American Indian / Alaska Native (AI) parents/guardians of adolescents who reside in urban areas. This will be a multi-regional effectiveness trial across four regions: Northeast (Buffalo/Niagara), Midwest (St. Paul/Minneapolis), Mountain (Denver), and Southwest (Phoenix). There are four specific aims. First, this study will test the effectiveness of Parenting in Two Worlds (P2W) as compared to an informational family health intervention, Healthy Families in 2 Worlds (HF2W), in improving parenting and family functioning. Second, this study will test if the relative effectiveness of P2W, compared to HF2W, varies by parent's/guardian's level of socioeconomic vulnerability, experiences of historical loss, or AI cultural identity. Third, this study will examine if P2W can reduce adolescent (ages 12 - 17) risky health behaviors including substance use, depressive symptoms, suicidality, and risky sexual behaviors. Fourth, this study will examine whether positive changes in parenting and family functioning that result from P2W lead to positive changes in adolescent's health behaviors.

This description comes directly from the study's public registry record.

Talk to the study team

Stephen S Kulis, PhD  ·  480-285-7419  ·  kulis@asu.edu

Christine McCaleb, MA  ·  602-496-0261  ·  christine.mccaleb@asu.edu

Always discuss trial participation with your own doctor first.

Locations (4)

Phoenix Indian CenterPhoenix, Arizona, United StatesRecruiting
Denver Indian CenterDenver, Colorado, United StatesRecruiting
Ain Dah Yung CenterSaint Paul, Minnesota, United StatesRecruiting
Native American Community Services Erie and Niagara CountiesBuffalo, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06324318