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Study identifier: NCT06323837 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Mirtazapine for the Treatment of Methamphetamine Use in Opioid Use Disorder Patients Receiving Medication Assisted Treatment

Condition: Stimulant Use Disorder  ·  Sponsor: Washington State University

PhasePhase 2
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

This project will evaluate the ability of Mirtazapine (MZP), a pharmacologically unique medication with a growing body of evidence to support its efficacy and safety for the treatment of methamphetamine (MA) use among medication for opioid use disorder (MOUD) patients, to significantly decrease MA use and related health-impairing behaviors. MZP has already successfully been used in the treatment of methamphetamine (detailed further below and in the Appendices). The investigators hypothesize that those assigned to the MZP plus treatment as usual (TAU) MZP+TAU arm will demonstrate significantly increased rates of biochemically verified abstinence from MA and other substances of abuse and experience improvements in health impairing behaviors relative to the placebo (PLO)+TAU arm across the 10-week treatment and follow-up periods.

This description comes directly from the study's public registry record.

Talk to the study team

Research Coordinator  ·  (509) 638-2376  ·  wsu.appl@wsu.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Spokane Treatment CenterSpokane, Washington, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06323837