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Study identifier: NCT06323668 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Cardiac Implantable Electronic Device RemOval Versus Full CoUrse Medical Treatment

Condition: Cardiac Implantable Electronic Device Infection  ·  Sponsor: Rigshospitalet, Denmark

PhaseNA
Planned participants180
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

The CIEDOUT study is an open label randomized trial in patients with possible cardiac implantable electronic device (CIED) infection. The hypothesis is that CIED removal + guideline antibiotic therapy is better than 6-weeks antibiotic therapy alone in preventing death or relapse of bacteremia in patients with bacteremia and possible CIED infection (not definite CIED infection). The objective of this study is to test whether CIED removal + guideline antibiotic therapy is superior to 6-weeks antibiotic therapy alone in prevention of the composite endpoint of death or relapse bacteremia after 6 months of follow-up in patients with CIED and systemic infection but without definite CIED infection.

This description comes directly from the study's public registry record.

Talk to the study team

Emil L Fosbøl, MD, PhD  ·  +4535456340  ·  emil.fosboel@regionh.dk

Amna Alhakak, MD  ·  amna.alhakak.01@regionh.dk

Always discuss trial participation with your own doctor first.

Locations (1)

Copenhagen University Hospital, RigshospitaletCopenhagen, DenmarkRecruiting

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Source record: clinicaltrials.gov/study/NCT06323668