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Study identifier: NCT06322212 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Type 2 Diabetes and Blood Brain Barrier Improvement

Condition: Type2diabetes  ·  Sponsor: University of California, Los Angeles

PhaseEARLY_Phase 1
Planned participants52
Who can joinAll sexes, 40 Years to 65 Years
Healthy volunteersNo

About this study

The majority of T2DM adults show thiamine (vitamin B1) deficiency which may contribute to impaired function. This study will examine patients with T2DM through brain MRI scans, cognition assessments, blood tests, and questionnaires. Our goal is to see if a thiamine treatment (taking vitamin B1 capsules) can improve function. Patients will be asked to come to UCLA two times three months apart and each visit will last about 2.5-3 hours.

This description comes directly from the study's public registry record.

Talk to the study team

Rajesh Kumar, PhD  ·  310-206-1699  ·  rkumar@mednet.ucla.edu

Dineth R Karunamuni, MS  ·  856-701-5332  ·  dkarunamuni@mednet.ucla.edu

Always discuss trial participation with your own doctor first.

Locations (1)

UCLALos Angeles, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06322212