Condition: Pulmonary Embolism · D-dimer · Diagnosis · Sponsor: Dr. Kerstin de Wit
It is important to diagnose pulmonary embolism in a timely manner to prevent death and long-term disability. More than half a million people (4-5% of emergency department patients) are tested for pulmonary embolism, although the positive rate is low. Imaging for PE testing exposes patients to radiation, is expensive, adds time to the emergency visit, and can lead to a false positive diagnoses. Existing protocols aimed at reducing unnecessary pulmonary embolism imaging are complex and seldom used by emergency physicians. Too many patients undergo unnecessary pulmonary embolism imaging. A new tool (called Adjust-Unlikely) could safely reduce pulmonary embolism imaging in Canada. A research group composed of researchers, emergency physicians, and patients developed the Adjust-Unlikely clinical decision rule: a rule which has been customized for emergency physicians and emergency patients. Adjust-Unlikely is highly sensitive at the bedside, meaning there are very few false negative results. The study aim is to prospectively validate Adjust-Unlikely pulmonary embolism testing in emergency patients with suspected pulmonary embolism.
This description comes directly from the study's public registry record.
Natasha S Clayton · 416-566-3590 · natasha.clayton@queensu.ca
Always discuss trial participation with your own doctor first.
| Hamilton Health Sciences Corporation | Hamilton, Ontario, Canada | Recruiting |
| Kingston Health Sciences Centre | Kingston, Ontario, Canada | Recruiting |
| London Health Sciences Centre Research Inc | London, Ontario, Canada | Active Not Recruiting |
| Ottawa Hospital Research Institute | Ottawa, Ontario, Canada | Active Not Recruiting |
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Source record: clinicaltrials.gov/study/NCT06320236