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Study identifier: NCT06319027 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Identifying Findings on Brain Scans That Could Help Make Better Predictions About Brain Cancer Progression, The GABLE Trial

Condition: Glioblastoma, IDH-Wildtype  ·  Sponsor: ECOG-ACRIN Cancer Research Group

PhasePhase 2
Planned participants100
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase II trial studies whether different imaging techniques can provide additional and more accurate information than the usual approach for assessing the activity of tumors in patients with newly diagnosed glioblastoma. The usual approach for this currently is magnetic resonance imaging (MRI). This study is trying to learn more about the meaning of changes in MRI scans after treatment, as while the appearance of some of these changes may reflect progressing tumor, some may be due the treatment. Dynamic susceptibility contrast (DSC)-MRIs, along with positron emission tomography (PET) and/or magnetic resonance (MR) spectroscopy, may help doctors tell which changes are a reflection of the treatment and which changes may be due to progressing tumor.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (12)

Cedars-Sinai Medical CenterLos Angeles, California, United StatesRecruiting
Baptist MD Anderson Cancer CenterJacksonville, Florida, United StatesRecruiting
Moffitt Cancer CenterTampa, Florida, United StatesRecruiting
University of Michigan Rogel Cancer CenterAnn Arbor, Michigan, United StatesRecruiting
Carolinas Medical Center/Levine Cancer InstituteCharlotte, North Carolina, United StatesRecruiting
Duke University Medical CenterDurham, North Carolina, United StatesRecruiting
Wake Forest University Health SciencesWinston-Salem, North Carolina, United StatesRecruiting
Rhode Island HospitalProvidence, Rhode Island, United StatesRecruiting
Edwards Comprehensive Cancer CenterHuntington, West Virginia, United StatesRecruiting
West Virginia University HealthcareMorgantown, West Virginia, United StatesRecruiting
University of Wisconsin Carbone Cancer Center - Eastpark Medical CenterMadison, Wisconsin, United StatesRecruiting
University of Wisconsin Carbone Cancer Center - University HospitalMadison, Wisconsin, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06319027