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Study identifier: NCT06318260 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Haemodynamic Effects of Dobutamine in Patients With Wild-type Transthyretin Amyloid Cardiomyopathy (ATTRwt)

Condition: ATTR Amyloidosis Wild Type  ·  Sponsor: Steen Hvitfeldt Poulsen

PhasePhase 1/Phase 2
Planned participants15
Who can joinAll sexes, 65 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to test the effects of the inotropic drug named dobutamine, in patients with wild-type Transthyretin Amyloid Cardiomyopathy (ATTRwt). The main questions it aims to answer are: * What are the effects of increasing dosages of dobutamine infusion on cardiac output and filling pressures in patients with symptomatic ATTRwt. * Safety of dobutamine infusion in this patient population. Participants will receive increasing doses of dobutamine infusion, and the effects on cardiac output and filling pressures will be assessed simultaneously by echocardiography and right heart catheterization.

This description comes directly from the study's public registry record.

Talk to the study team

Ali Hussein Jaber Mejren, MD  ·  0045 91 65 18 48  ·  alimej@clin.au.dk

Steen Hvitfeldt Poulsen, MD,PhD,DMSci  ·  steepoul@rm.dk

Always discuss trial participation with your own doctor first.

Locations (1)

Department of Cardiology, Aarhus University HospitalAarhus, DenmarkRecruiting

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Source record: clinicaltrials.gov/study/NCT06318260