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Study identifier: NCT06316960 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Safety and Efficacy of Avapritinib in Relapsed or Refractory Pediatric CBF-AML With KIT Mutation

Condition: AML, Childhood · Relapse/Recurrence · Refractory AML  ·  Sponsor: Children's Hospital of Soochow University

PhasePhase 2
Planned participants50
Who can joinAll sexes, N/A to 18 Years
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the efficacy and safety of avapritinib in relapsed or refractory pediatric core binding factor acute myeloid leukemia with KIT mutation.

This description comes directly from the study's public registry record.

Talk to the study team

Shaoyan Hu, MD, PhD  ·  +86-13771870462  ·  hsy139@126.com

Li Gao, MD  ·  +86-15821963190  ·  joygaoli@163.com

Always discuss trial participation with your own doctor first.

Locations (12)

First Affiliated Hospital Of University of Science and Technology of ChinaHefei, Anhui, ChinaNot Yet Recruiting
The Second Hospital of Anhui Medical UniversityHefei, Anhui, ChinaNot Yet Recruiting
Guangzhou Women and Children Medical CenterGuangzhou, Guangdong, ChinaNot Yet Recruiting
The First Affiliated Hospital of Guangxi Medical UniversityNanning, Guangxi, ChinaNot Yet Recruiting
Kaifeng Children's HospitalKaifeng, Henan, ChinaNot Yet Recruiting
The First Affiliated Hospital of Zhengzhou UniversityZhengzhou, Henan, ChinaNot Yet Recruiting
Third Xiangya Hospital of Central South UniversityChangsha, Hunan, ChinaNot Yet Recruiting
XiangYa Hospital Central South UniversityChangsha, Hunan, ChinaNot Yet Recruiting
Children's Hospital of Soochow UniversitySuzhou, Jiangsu, ChinaRecruiting
Xuzhou Children's HospitalXuzhou, Jiangsu, ChinaNot Yet Recruiting
Qilu Hospital of Shandong UniversityJinan, Shandong, ChinaNot Yet Recruiting
Children's Hospital Of Fudan UniversityShanghai, Shanghai Municipality, ChinaNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06316960